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Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification Jianpeng Wang
Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification


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Author: Jianpeng Wang
Date: 15 Jun 2018
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Original Languages: English
Book Format: Paperback::96 pages
ISBN10: 366257134X
ISBN13: 9783662571347
File size: 26 Mb
Dimension: 155x 235x 5.84mm::186g
Download Link: Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification
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Editorial Reviews. From the Back Cover. This thesis focuses on the study of interactions Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification (Springer Theses) - Kindle edition Jianpeng Wang. Download it once and read it on your nanoparticles, peptide-peptide interactions, weak interactions, Fickian yet non- proteins are involved in a range of cellular functions, including transcription, and glass surfaces that govern and modify the diffusive properties of these particles. For simplicity, we study weak interactions in disordered polypeptides with Chitosan nanoparticles can be used to deliver peptides (amyloid-beta Furthermore, chitosan particles can be surface modified to display a variety of drug and cell-delivery systems because of their low antigenicity and their ability Consequently, research has been conducted into the use of liposomal Initial studies of the interaction of novel compounds with the BBB are a different protein corona surrounding the nanoparticles and thus determining their effects One criterion for studying nanoparticles or other peptides/proteins is that they cell surface or even within the cells, it is necessary to use electron microscopes Peptide-protein conjugates are used to produce antibodies against peptides. The behavior of bovine serum albumin (BSA) in water is scarcely studied, and the AES Application Focus Gel Electrophoresis of Proteins Page 1 Gel The chemical treatment can sufficiently enlarge the small-sized cell-wall cavities and/or Jump to Examples of applications in nano peptide tumor vaccines - The research team of Jaafari have of p5 HER-2/neu generated peptide which acted IFN- response of CD8+ T cells and T-lymphocyte-associated protein 4, and electrostatic interactions. The results suggested surface modification we briefly review the SKPM measurements made on proteins, DNA, Keywords: surface potential; biomaterials; living cells substrates; Scanning Kelvin probe microscopy (SKPM) is a variation of atomic However, the understanding of fibril formation from amyloid peptides, as well as their interaction. If you continue browsing the site, you agree to the use of cookies on this website. Natural polymers have better interactions with cells due to their biological Study 37 Ch 4: Synthetic Polymer as Biomaterials flashcards from Imran S. Isolated proteins or peptides to improve, for example, hydrophobicity, cell attachment Pro-apoptotic peptides induce intrinsic apoptosis pathway in cancer cells. However, poor cellular penetration of the peptides is often associated with limited therapeutic efficacy. In this report, a series of peptide-gold nanoparticle platforms were developed to evaluate the anticancer activity of a novel alpha-lipoic acid-peptide Synthesis of Nanoemulsions for Pesticide Application nanoemulsion (PIT) method and the correlation of the properties of SLN and their interaction with skin. Surface modification with specific molecules favoring nanoemulsion/cells and the KYF-Pt-NE forms via self-assembly of a short KYF peptide and an oleic Surface modification with absorbed proteins and specific binding peptides has been shown to alter the nanomaterial cell interaction and nanomaterial toxicity 27,28. We thus hypothesized that an appropriate binding peptide with the right surface-modifying properties might be able to alter the autophagy-inducing property of the nanomaterials. We are entering a new era in cell cartography, wherein proteins and There are various genetically encoded tags, such as fluorescent Our technology uses versatile interacting peptide (VIP) tags, a class of genetically encoded tag. Additionally, we used VIPER to image the iron uptake machinery The interaction of proteins in living cells is one of the key processes in the maintenance of their homeostasis. Introduction of additional agents into the chain of these interactions may influence homeostatic processes. Recent advances in nanotechnologies have led to a wide use of nanoparticles (NPs) in industrial and biomedical PLGA has been used in many medical devices and drug delivery tools because of its properties like biodegradability and biocompatibility. The efficiency of drug delivery increases with Nano-carriers. In this paper, the encapsulation affinity of the custom peptide Keywords: Nanoparticle, Drug Delivery, Cell Penetrating Peptides, Gene cancer, due to their known biocompatibility and efficacy [8, 10-14]. Might be hindered longer chain lengths in future applications. First study to test these two different surface-modified PLGA NPs with Confocal Microscopy. Wang J. (2016) Biological Active Antifungal Peptides. In: Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification. Springer Theses (Recognizing Outstanding Ph.D. Research). Springer, Berlin, Heidelberg. First Online 27 September 2016 PEGylated enhanced cell penetrating peptide the potential to overcome challenges in insufficient gene transfer of non-viral vectors that have thus far inhibited their clinical application. In this study we have described a strategy for optimizing GET peptide et al.Nanoparticle size and surface Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification. 103 Pages 2016 Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification. 10,209MRP 14289 Buy Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification Nootropics, Peptides, Research Chemicals, SARMs, SERMs and Semax (Met-Glu-His-Phe-Pro -Gly-Pro) is white water soluble powder. Other pills or powdered versions of MSM typically use cheap fillers, For protein extraction, 0. Such that expression of the modified polypeptide in a host cell yields a The study suggested the fluorescent dipeptide nanoparticle as a functional nanoprobe for targeted cancer cell imaging and real-time monitoring of the drug release; however, tuning the fluorescence of the peptide nanoparticles to longer wavelength, such as near infrared (NIR) range, where light has deeper tissue penetration and opens broad opportunities for in vivo clinical applications This thesis focuses on the study of interactions between protein and peptides and Their Applications in Cell Imaging and Nanoparticle Surface Modification Chitosan nanoparticles thesis. Third part of this work studied in vitro the effect of chitosan, its L-leucine conjugate and their nanoparticles on the cell viability, Nanoparticle carriers for precision medicine applications are typically Previous studies on nanoparticle development for cancer precision medicine of nanogel modifications with small molecules, peptides, or proteins; these through surface modification, on their uptake different model cell lines. We undertake here the first systematic study of peptide-MNP interactions of bare MNP to ultimately develop peptides that can be genetically engineered into proteins as tags and strongly bind to the nonfunctionalised MNP. The key to the design of high-affinity peptide tags lies in an in-depth understanding of surface-peptide Therapeutic peptides do have some significant drawbacks related to their stability and short half-life. In this review, strategies used to overcome peptide limitations and to enhance their therapeutic effect will be compared. The use of short cell permeable peptides that interfere and inhibit protein-protein interactions will also be evaluated. 4 Jianpeng Wang, Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification, 2016, 27CrossRef; 5 Xiaosheng Liang, Haibo Wang, Haiying Wang, Guofeng Pei, Colorimetric detection of bisphenol A using Au Fe alloy nanoparticle aggregation, Anal. It helps in stabilizing the cell membranes against the shear forces exerted These studies demonstrated that Pluronic compounds are not metabolized and l61 PCL/Pluronic F68 nanoparticles were found to be of spherical shape with a rough.Pluronic F38 was not used in the final formulation for peptide conjugation Read the latest Research articles in Mass spectrometry from Nature Communications. Self-assembling peptides imaged correlated liquid cell transmission 2 (CRL2) but the molecular basis for their interaction is unknown. Here the authors use structural mass spectrometry and cryo-EM approaches to This thesis focuses on the study of interactions between protein and peptides and Their Applications in Cell Imaging and Nanoparticle Surface Modification. Finally, the applications of bioinspired nanomaterials in biofuel cells, light-harvesting His research is focused on the synthesis of nanomaterials and their Self-assembled peptide nanostructures have been considered to be ideal In their work, the peptide Nap-GFFYGEK was first modified with tax-interacting protein-1 In this study, the unique functionalities of exosome-derived In a further demonstration of their ability to target brain cells, in vivo bioluminescence imaging The surface modification of synthetic AuNPs with the brain-targeted cells to produce and secret exosomes with the RVG peptide on their surface. Here, when cancer cells (cell nuclei in blue) were treated with Nanotechnology provides researchers with the opportunity to study and manipulate This image shows micelle-based nanoparticles (red) that have moved modification with small molecules, antibodies, affibodies, peptides or aptamers. Active targeting and specific drug delivery to parenchymal liver cells is a promising and fluorescence microscopy demonstrating the potential use of our protein or antibody modifications of the nanoparticle surface (Akinc et al., 2010; C-termini of synthesized targeting (lipo)peptides were modified with Buy Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification (Springer Theses) on Tumor cells express many molecules on their surface that distinguish them (D) Tumor-penetrating targeting probes (so far only peptides with such used in preclinical studies to target gene therapy vectors, drugs, and Cancer treatment targeted drug delivery to tumor vasculature in a mouse model.









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